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, 1994). CoVs genomic RNA replication is mediated by RNA-directed RNA polymerase (Pol/RdRp) and that is also liable for transcription on the viral RNA genome. There may be experimental proof for SARS-CoV that nsp7 and nsp8 activate and confer processivity for the RNA-synthesizing exercise with the polymerase (Walls et al., 2000). The synthesis of s
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